22nd Century Frontier®

22nd Century Frontier®

The Most Active 780+ Seed Stave VC Funds (US) 💰

Exclusive Database: 780+ Most Active US Seed Stage VC Funds - For Premium Subscribers Only

Petar Dimov's avatar
Petar Dimov
Dec 22, 2025
∙ Paid

Here’s the brutal reality:

Seed funding is becoming a power-law game.

The top 55 seed investors closed 1,138 deals in 2024, but that’s just 29% of all US seed investments - meaning 71% of seed capital flows through smaller, less visible funds that founders never pitch to.

Yet founders still chase the same 20 mega-names: Y Combinator, Sequoia, Accel, Andreessen Horowitz, etc.

The result?

Rejection pipelines, wasted runway, and missed checks from 760+ funds actively writing seed checks.

The numbers tell the story.

In Q3 2025, seed-stage investment hit $4.6 billion in the US alone, down 25% sequentially, though still 14% ahead YoY.

Yet fewer deals are getting done overall; concentration is accelerating as mega-rounds ($100M+) drain capital from Series A and Series B, pushing quality founders earlier - straight into seed.

This creates opportunity.

The barrier?

Discovery.

Traditional databases surface mega-funds first.

Smaller vehicles?

Buried, outdated, or invisible.

We’ve solved this.

The 780+ US Seed Stage VC Database maps every active seed investor by:

Firm Name, City, State
Top 5 Investment Sectors
Stage (Seed, Early Stage, Late Stage)
Website, LinkedIn, Crunchbase Profiles

Identify intro targets.

Land meetings faster.


Get Instant Access

Unlock the full searchable database as a 22nd Century Frontier premium subscriber.

👇 Subscribe Now to access also:

✅ The US Micro VC Map🗺️: 600+ Funds Backing Early-Stage Founders💰
✅ 🚀 Inside the Minds of VCs: How UK Funds Evaluate Startups: Part I, Part II, Part III, and Part IV
✅ All Premium Resources
✅ Full Archive

& more

The unfair advantage is here.

Target smarter.

Close faster.

Here are the most active 780+ Seed VC Funds 👇

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