22nd Century Frontier®

22nd Century Frontier®

100 Active US VCs Investing from Pre-Seed to Series A: The Database Every Early-Stage Founder Needs 🚀

Exclusive Database: Access the VCs actively backing companies from idea to scale

Petar Dimov's avatar
Petar Dimov
May 13, 2026
∙ Paid

If you’re pitching late-stage VCs when you need pre-seed or Series A capital, here’s the hard truth:

You’re pitching to the wrong funds.

Early-stage VCs operate differently.

They write checks before you have revenue.

They back conviction, not spreadsheets.

And in 2025, they delivered.

US venture capital deal value surged to $339.4 billion, approaching 2021’s peak of $358.2 billion.

Early-stage funding hit £25.7 billion in Q4 2025 alone, the highest quarterly total since Q4 2021.

The numbers tell the story.

US seed funding totaled $19.4 billion in 2025, with the median seed round at $3.1 million.

Median pre-money valuations climbed to $16 million in Q1 2025, up 18% year over year.

Series A rounds ranged from $12 million to $18 million, signaling strong appetite for companies demonstrating early traction.

But here’s the challenge:

AI captured 65.4% of total US VC deal value in 2025 and 39.4% of all deals, creating unprecedented concentration.

At seed stage, 42% of global funding went to AI companies, up from 30% in 2024.

If you’re not in AI, you need precision targeting to find the right VCs.


✅ What You’re Getting

A verified, curated database of 100 active US VCs investing from pre-seed to Series A in 2024-2025:

Firm Name

Description (thesis, focus, track record)

Location (city and state)

Inception Year

Type Fund

Investment Focus (sectors, verticals)

Investment Stage (pre-seed, seed, Series A)

Examples of Portfolio Companies

Contact details (Representative, Email, Website, LinkedIn, X, Facebook, and more)

This isn’t a random list.

These are VCs actively deploying capital across sectors, stages, and geographies.


🔥 Why This Changes Your Fundraise

🎯 Target VCs whose stage, sector, and check size match your round

🚀 Skip funds that won’t lead and connect with decision-makers who write checks

📈 Access contact details and representatives to accelerate warm intros

Early-stage VCs don’t just fund.

They set you up for Series B, connect you to customers, and validate your market.

US startups captured $18 billion in seed funding in 2025, representing 50% of global seed investment.

The right VC is your gateway to that capital.


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